Periarticular bone density and trabecular morphology predict knee oa structural progression

Knee OA, biomechanics, and progression to TKA

Osteoarthritis (OA), the most prevalent type of arthritis, is characterized by damage to articular cartilage, a protective layer over the ends of bones, leading to changes in other joint structures (bones, ligaments, muscles, and nerves) that subsequently result in pain, stiffness, and functional disability in adults.1 OA is common at the knee joint, more so in the medial tibiofemoral compartme...

Preoperative Periarticular Knee Bone Mineral Density in Osteoarthritic Patients Undergoing TKA

BACKGROUND Preoperative periarticular bone quality is affected by joint loading. The purpose of this study was to determine the periarticular bone mineral density of the knee joint of patients undergoing total knee arthroplasty, and whether the location of the load-bearing axis correlates with the measured bone mineral density. MATERIALS AND METHODS The bone mineral densities of the medial an...

Effect of pulsed electromagnetic field stimulation on knee cartilage, subchondral and epyphiseal trabecular bone of aged Dunkin Hartley guinea pigs.

It has been demonstrated that pulsed electromagnetic field (PEMF) stimulation has a chondroprotective effect on osteoarthritis (OA) progression in the knee joints of the 12-month-old guinea pigs. The aim of the present study was to discover whether the therapeutic efficacy of PEMFs was maintained in older animals also in more severe OA lesions. PEMFs were administered daily (6 h/day for 6 month...

Knee injury and knee OA

Varus-valgus Alignment in the Progression of Knee Oa

Introduction. Most of the epidemiologic literature concerning OA deals with risk factors for the initial development of arthritis. However, in a large subset of people, knee OA remains a relatively mild condition. The form of knee OA responsible for the bulk of individual and societal cost is OA that progresses beyond mild stages. Identification of factors responsible for progression is critica...